The cat's went to the veterinarian today for check ups, vaccination and a prescription for a kitty downer for the trip. They both meowed quite a bit at first, Zoe stopping after a couple blocks. Once at the vet, Simba kept meowing and started to get hoarse.
Zoe, on the other hand, buried herself into the cat bed in her carrier and looked at me with eyes that said, "I trusted you!"
Other than a semi-truck honking its horn as we were leaving the vet office, freaking out both cats, everything went great. I thought they would be mad when we got home but they're acting normal, Zoe isn't even trying to hide and Simba hasn't peed on anything. Success!